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Mitochondria in the control group consistently showed a decrease in size and an increase in membrane density according to TEM imaging

Taga ME, Larsen NA, Howard-Jones AR, Walsh CT, Walker GC (2007) BluB cannibalizes flavin to form the lower ligand of vitamin B 12

Zeller et al

Despite its lower reactivity, HO becomes highly damaging in the presence of transition metals such as iron or copper, where it can generate the highly reactive hydroxyl radical (OH) [28]