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[12] The injectable powder sold in research vials is neither an approved drug nor a cosmetic in the regulatory sense

The results showed that after FOXO4-DRI treatment, the p-P53/P53 ratio significantly increased in the nucleus, cytoplasm, and total protein samples (Figure 5D)

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Plasma was isolated by centrifugation at 17,000 g for 5 min at 4 C and diluted 1:10 in 50% (v/v) glycerol in PBS (pH 7.4) (Sigma-Aldrich) for storage at 20 C until analysis