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Extracellular vesicles, also known as exosomes (EXOs), have been increasingly recognized as a promising tool for mitigating tendon aging, with potential applications in tissue regeneration and repair (9), and the purified exosomes can also improve the biomechanics of the rotator cuff (149)

EMBO J 20:18401849 Liebschner D, Afonine PV, Baker ML, Bunkczi G, Chen VB, Croll TI, Hintze B, Hung LW, Jain S, McCoy AJ et al (2019) Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

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The HIV protease, after folding at pH 3.5, exhibits fair solubility up to pH 5.0, with solubility decreasing at higher pH values