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This does not mean every patient with autism has a creatine deficiency, but it provides a plausible biochemical connection between methylation demand and poor energy resilience

The study of Meguid et al., involved 30 healthy children and 30 children affected by autism (18 males, 12 females), aged 311 years, all diagnosed with DSM-V and CARS, with no reported medical comorbidities and in good physical health

Biochim Biophys Acta;180010111320 164

Some people may have normal carnitine levels while others may have low levels caused by a genetic problem or certain condition that affects the body's ability to produce or absorb it