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Hence, the application of nanotechnology could enhance the efficacy and improve their bioavailability by increasing solubility, enhancing plasma half-life, preventing degradation in the intestinal environment, and elevating permeation in the small intestine (Hu et al., 2017)

Clinical Anatomy, 28(6):706-16

Science (New York, N.Y.) 284, 505507 (1999)

Revised: 4/2026 Full Prescribing Information WARNING: LIFE THREATENING ADVERSE REACTIONS General Population: Hepatic failure resulting in fatalities has occurred in patients receiving valproate and its derivatives