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A.BroekhuizenR.EverettH.AgostiniL.KuijkL.MartinonF.et al (2007)

Each of these pathways contributes to the cells ability to respond to oxidative signals effectively

On the one hand, an overabundance of ROS activates multiple transcription factors, such as NF-B and Nrf2, thereby inducing the synthesis of proteins that govern inflammation, cellular transformation, cell viability, proliferation, invasion, angiogenesis, and metastasis