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After consulting all the scientific literature available on this subject at the time, it observed that the results of the various work had to be treated with caution, particularly because only 20 studies out of the 843 identified had followed the peer review scientific validation process

It's implied the others do as well

This substance causes, among others, an increase in the respiratory rate, blood pressure and heart rate, and also promotes a tendency toward blood clotting, which increases the risk of thrombosis [2, 3]

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