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Raw sequence data were demultiplexed using QIIME 1, and amplicon sequence variants (ASV) were inferred using the DADA2 pipeline

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This proposed standard for alternatives to office visits is similar to several requirements tested in CMS Innovation Center models (such as the CPC+ model's requirement that participating practices regularly offer at least one alternative to traditional office visits [60] ), and reflects the understanding that providing alternatives to traditional office visits is an essential element of the delivery of care under an advanced primary care model of care

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