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This cellular demise can subsequently diminish ECM synthesis, which in turn, exacerbates the degradative changes within the IVD microenvironment, perpetuating a cycle that further compromises the viability of NPCs

Plasma homocysteine concentration predicts mortality in noninsulin-dependent diabetic patients with and without albuminuria

Questa soppressione di vitale importanza nelle ferite croniche e nell' invecchiamento cutaneo (inflammaging) , dove l'infiammazione persistente degrada la matrice extracellulare e impedisce la corretta riepitelizzazione