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But current evidence suggests that it may play an important role in maintaining optimal health and wellness

The downregulation of OCTN2 activity and protein expression in the kidney reduces the reabsorption of carnitine in the kidney, leading to a decrease in carnitine availability in the liver and causing hepatic lipid metabolism disorders [260]

However, while no difference in the fold reduction of the biofilm biomass was noted in the presence of 1 mM pyruvate, the biofilm biomass was reduced by less than 2-fold in the presence of 10 mM pyruvate

Description For laboratory procurement and specifications, visit: Mechanism (Research Context) Carnitine Shuttle: Facilitates transport of long-chain fatty acids across the inner mitochondrial membrane for -oxidation, supporting ATP supply during endurance work