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Redox repair of the oxidised forms (ergothioneine disulfide and 5-oxo-ergothioneine) of ergothioneine can be rapidly provided by ascorbate (Reference Asmus, Bensasson and Bernier48) or can be achieved enzymatically by either glutathione reductase in presence of glutathione, or the selenoenzyme thioredoxin reductase (Reference Jenny, Mose and Haupt50)

The predicted LLPS state by Model II is denoted by the region between the two vertical dashed lines

On the day of measurement, mice were orally administered metformin at a dose of 150 mg/kg 2 h after the start of fasting, and FDG was injected 2 h later

14,15-EET inhibited rat mesenteric arterial endothelial senescence, down-regulated p53 expression in aged endothelial cells and improved the impaired endothelium-dependent vasodilatation in aged rats through activation of mTORC2/Akt signaling pathway (Yang et al., 2014)