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This mechanistic insight is strongly supported by in vivo evidence showing that anti-OPN antibodies, which mimic the effect of blocking thrombin-cleaved OPN, replicate a tumor suppression phenotype in knock-in mice engineered with a thrombin cleavage-resistant form of the protein [271]

It can injure the mitochondria, which is the energy producing cells

What we DO know, however, is that only 20% (or even less) of the people with symptomatic B12 deficiency have anaemia or altered size of the red blood cells

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