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In case of severe infections with Trichuris suis, the animals should be treated for 10 days

at China Pharmaceutical University and Nanjing First Hospital: oral Dihexa restored spatial learning and memory in the APP/PS1 transgenic mouse model of Alzheimers disease via the PI3K/AKT signaling pathway, reduced neuroinflammation, and preserved hippocampal synaptophysin expression (Sun et al., Brain Sciences 2021)

[PubMed: 16675541] 31

Overexpression of p21 alone may also be sufficient to inhibit ferroptosis via interaction with cyclin dependent kinases (CDKs) in some contexts (Venkatesh et al, 2020b)