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2.12 Homology modelling of UA transporters The transporters of URAT1, GLUT9, OAT1, and ABCG2 lack structural information ( 2.13 Molecular docking The proteins URAT1, GLUT9, OAT1 and ABCG2 were employed as receptor models, whereas Saikosaponin A, Tanshinone IIA, Schisandrol B and Ganoderic acid A served as ligand molecules, representing the active constituents in the drug-containing sera of Wuling capsule

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Importantly, this interaction seems to be critical for Mtb pathogenicity and dissemination in vivo: animal experiments with Mtb infection showed that Mtb harboring a PtpA mutant incapable of interacting with PRMT6, as well as Mtb ptpA , was less able to cause pathogenicity and dissemination in the mouse lung than wild-type Mtb

Spirulina also provides essential minerals like zinc, iron, calcium, magnesium, potassium, selenium, sodium, and molybdenum