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Most significantly, chemicals in tobacco smoke (including nicotine) restrict blood circulation, altering the bodys ability to absorb essential nutrients

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You should telephone BPAS on 0300 333 68 28 for advice if: 24 hours after taking the misoprostol, you do not bleed at all, have spotting / only see blood on a tissue when wiping (see Minimal image 1) You experience flooding or heavy bleeding soaking 2 maternity pads or thick overnight pads for 2 hours in a row (see Heavy image 4) Call 999 if you experience very heavy bleeding (see Flooding image 5) and feel unwell Prolonged moderate to heavy bleeding can lead to significant blood loss and anaemia so please get in touch if this occurs