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"Given that tobacco use is still the leading cause of preventable disease and death in the U.S., there's a lot at stake to ensure the public understands these risks." Erika Sward, assistant vice president of national advocacy for the American Lung Association, told NPR's Richard Harris, the warnings are "critically needed and long overdue." The organization sued the FDA to compel it to produce warning labels after the agency's first efforts failed

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In the comparison of the new GWLs with neutral pictures, smokers after smoking showed increased BOLD responses especially in subcortical, temporal and frontal regions including amygdala/parahippocampal gyrus, superior and middle temporal gyrus, e.g