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[113] Mutations in MMP1 gene that encodes for interstitial collagenase are associated with COPD

Among the regulations are: 1) prohibition of cigarettes, roll-your-own, and heated tobacco products with characterising flavourings, 2) mandatory health warnings on tobacco products, 3) prohibition of tobacco for oral use (does not apply to Sweden), 4) nicotine-containing liquid used to refill containers or disposable electronic cigarettes must not exceed a nicotine concentration of 20 mg/ml, 5) tanks for electronic cigarettes and disposables must not exceed 2ml e-liquid

This is likely due to the increased pressure in the stomach alongside a diet high in fatty, processed foods