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"Research has shown that the cardiovascular system reacts almost immediately to tobacco smoke - even one cigarette." She went on to say that smoking provides an immediate effect of things like a rise in heart rate and blood pressure, constriction of blood vessels, and a temporary reduction in oxygen delivery due to carbon monoxide exposure. This contributes to an increased risk in having a heart attack or stroke, as well as the risk of cancers of the lung, mouth, throat and oesophagus

Quantitative analysis of the percentage of the MAM to mitochondria (H), type of MAM apposition (I), and average length (J) of ER-mitochondria association (n = 5 mice per group, with 4 neurons per mouse)

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It protects from ageing, neurodegeneration and cancer13