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Conclusions TMT and RMT represent a promising and potential transformative approach to overcoming the challenges of drug delivery across the BBB

HIV-1 Nef expression in microglia disrupts dopaminergic and immune functions with associated mania-like behaviors

From the manufacturing perspective, this level of international reach usually indicates that a company has already developed systems capable of handling export documentation, regulatory standards, and cross-border logistics

Second, although the GeneCards database provided a focused and high-confidence set of disease targets for initial screening, future studies should employ an integrated multi-database approach (e.g., incorporating DisGeNET, OMIM, and TTD) to enhance the comprehensiveness of network pharmacology predictions