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Previous studies on changes in regional brain volumes in small samples, reporting different life-time exposure to nicotine, identified reduced volume in smokers in prefrontal areas but reported controversial results for other areas

It was surprising to see how consistent these findings were with our earlier research and with other studies from around the world, including from the U.K., Australia and Japan, among others, both in terms of the substantial risks associated with smoking and with the health benefits of quitting smoking, said lead study author Blake Thomson, M.Phil., D.Phil., an epidemiologist at the University of Oxford in Oxford, England