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Investigations for a very short time period in canine models and long-term cannulated mice exposed to concentrated air particles showed that hypertension was produced and that there was an indication of central sympathetic activation of the neuron system, presumably induced by neuro-inflammation in relation to the disclosure of PM 2.5 (190, 191)

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Reeve, a singer-actress who gave up some of her own career to be one of the nation's best-known caregivers, died late Monday at Memorial Sloan-Kettering Medical Center, said Kathy Lewis, president of the Christopher Reeve Foundation