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The categories acknowledge that evidence can be suggestive but not adequate to infer a causal relationship, and also allows for evidence that is suggestive of no causal relationship. Since the 2004 report, the individual chapter conclusions have consistently used this four-level hierarchy (Table 1.4), but evidence syntheses and other summary statements may use either the term increased risk or cause to describe instances in which there is sufficient evidence to conclude that active or involuntary smoking causes a disease or condition

Figure 2 Generating the starting population A representation of the U