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There is a study that has attempted to look at this, undertaken by some of my colleagues at University of Bristol (full disclosure, I am a member of the same research group as two of the authors of this paper)

Also, many people even use these to relieve stress or to help with quit smoking, Not only do these look extremely real, they even feel real

How to Deal with Your Cravings The first couple weeks after quitting can be rough and a woman may experience uncomfortable symptoms such as headaches, sleepiness, trouble focusing and mood changes

An allergist will need to perform a diagnostic test to determine if nicotine is the cause of their symptoms