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These observations were performed by three independent physiatrists who were blinded to the treatment groups, ensuring unbiased assessment

(February 2022)

Lactulose to mannitol ratio in humans The ratio of urinary excretion of lactulose to mannitol (LA/MA) was used to measure the intestinal mucosal permeability in ten RA patients and ten healthy controls who underwent colonoscopy, with higher ratios indicative of increased intestinal permeability as previously described 33

Supplementation with rumen-protected methionine or choline during the transition period influences whole-blood immune response in periparturient dairy cows