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Therefore, receptor-mediated transcytosis allows the specific targeting of larger drug molecules or drug-carrying particles (such as liposomes, polymer systems, nanoparticles) to the brain

Integrated metabolomics and lipidomics profiling of hippocampus reveal metabolite biomarkers in a rat model of chronic unpredictable mild stress-induced depression

To quantitatively assess the relationship of BRD4 and MLL4 binding partners, we measured binding affinities of BRD4 ET and MLL4 PHD2/3 to the region of ASXL1 containing both ASXL1 EBM and ASXL1 MBH (aa 564-635 of ASXL1, ASXL1 EBM-MBH ) (Fig

Rutin protects mercuric chloride-induced nephrotoxicity via targeting of aquaporin 1 level, oxidative stress, apoptosis and inflammation in rats