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These channels are responsible for regulating agonist affinity, ion selectivity, desensitization, and downstream signaling 2

Given the grave nature of the violations which have been committed and documented in this report and the pervasive climate of impunity for those crimes, Human Rights Watch has for years pushed the ICC prosecutor to undertake a formal probe consistent with the courts statute and welcomes the decision by the Prosecutor to seek arrest warrants in the situation in the State of Palestine

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