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The authors reported that severity of cardiac hypertrophy increases with E-cig exposure duration and vape nicotine content, whereas cardiac contractile function was not significantly altered

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For smoking intensity, the incidence rate ratio (IRR) was 1.13 (95% CI = 1.061.21), indicating that each one-category increase in initial e-cigarette frequency (e.g., from one to three uses in 6 months to monthly use) was associated with a 13 percent greater number of total cigarettes reported at the second assessment

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