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In a rat model simulating tyrosinemia type II through chronic L-tyrosine administration, NAC co-treatment effectively prevented the decline in ChAT activity in the cerebral cortex and partially reversed the increase in AChE activity in the hippocampus and striatum [120]

RadjabzadehDBoschJAUitterlindenAGZwindermanAHIkramMAvan MeursJBJet al

Following the injection, animals were monitored continuously during recovery and then daily for 72 h for any signs of discomfort, distress, or infection

18 Prevention Because of potential interactions from prolonged medication use, physicians should consider screening patients for vitamin B 12 deficiency if they have been taking proton pump inhibitors or H 2 blockers for more than 12 months, or metformin for more than four months