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A settler named James Rolfe was the first to successfully grow a tobacco cash crop for personal use and commercial sale at that time

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Cancer of the lung, mouth, nose, larynx, tongue, nasal sinus, oesophagus, throat, pancreas, bone marrow (myeloid leukaemia), kidney, cervix, ovary, ureter, liver, bladder, bowel and stomach Lung diseases such as chronic bronchitis and chronic obstructive pulmonary disease, which includes obstructive bronchiolitis and emphysema Heart disease and stroke Ulcers of the digestive system Osteoporosis and hip fracture Poor blood circulation in feet and hands, which can lead to pain and, in severe cases, gangrene and amputation Type 2 diabetes Rheumatoid arthritis