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Another possible reason is that severe nicotine dependence may accompany with intense pleasure, which may act as a protective role for the brain volume. The study continued: This current study confirms that brain volume atrophy appears to be more serious in smokers with higher levels of cigarette consumption and in smokers with moderate nicotine dependence, and nicotine dependence displayed contrary patterns on the brain volume of smokers compared with tobacco consumption

It reflects the cycle of addiction, where individuals make repeated attempts to quit but find themselves unable to overcome their tobacco dependence

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(In 2012 Kentucky farmers grew about 150 million pounds.) People aren't necessarily more likely to smoke if they live in a tobacco-growing state, but Kentuckians are certainly doing their part to help the local economy