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It shares the same robust steel construction, the same 15-pound activated carbon and zeolite foundation, and the same Medical Grade True HEPA core but the carbon blend in the HM450 is specially formulated with a greater proportion of impregnated carbon , designed to target a broader and more stubborn range of chemicals

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Journal of Alternative and Complementary Medicine 2012;18(9):8549

These 59 people were divided into 3 groups according to the frequency of hookah smoking: The total mean CEA in hookah smokers was practically no different from non-smokers, and was thus many times different from CEA measured in smokers (3.58 ng/ml versus 9.19 ng/ml)