Pomalidomide-5'-PEG1-C2-acid cell NRX-1532 acts as molecular glue

NRX-1532 acts as molecular glue in cells to promote the ubiquitylation and subsequent degradation of mutantbeta-catenin by the 26S proteasome

Cy3 carboxylic acid

Readily excited by the 546 nm spectral line from mercury-arc lamps used in fluorescent microscopes

75 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCC(O)=O)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Pomalidomide-5'-PEG1-C2-acid cell NRX-1532 acts as molecular glueDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Pomalidomide 5' PEG1 C2 acid Synonyms CAS Number 2412056 43 8 Related CAS Molecular Formula C18H19N3O7 Molecular Weight 389. 364 SMILES OC(=O)CCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping