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The time point of 60 min to determine oral bioavailability of the interventional product was decided based on the published t max of approximately 45 min after oral ingestion of NAC (Borgstrom and Kagedal, 1990) and that of approximately 75 min of glycine in blood plasma of healthy volunteers (Butterworth et al., 1958)

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10.1016/j.yrtph.2010.06.009 39 European Commission (2006)

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1 is a schematic depicting potential cellular conditions when storing/preserving organs in a solution containing optimal concentrations of sodium, chloride, magnesium, sulfonic acid, saccharic acid, and glutathione (GSH)

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