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Nevertheless, some experts have recommended that long-term treatment with thiols should be used in patients with exacerbation phenotype without chronic bronchitis, particularly in those with early stages of COPD with less severe airway obstruction, bronchiectasis with COPD overlap phenotype, and bronchitic phenotype with or without history of exacerbation [105]

Statistical difference between multiple groups were analyzed by one-way ANOVA and P 4) was performed to further explore which bacteria were significantly affected by QCHS

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These data strongly suggest that induced ferroptosis can result in PE-like manifestations in pregnant rats