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Mitoplastsrather than mitochondriashould be subjected to RNase treatment before lysis in order to minimize the risk of contamination

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Lack of ligand causes the binding of corepressors to the transcriptional complex, ultimately inhibiting the transcription of target genes (Figure 1)

Int J Clin Exp Pathol 3(5):505 Kurikawa N, Takagi T, Wakimoto S, Uto Y, Terashima H, Kono K, Ogata T, Ohsumi J (2013) A novel inhibitor of stearoyl-CoA desaturase-1 attenuates hepatic lipid accumulation, liver injury and inflammation in model of nonalcoholic steatohepatitis