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From the first arrival of kidnapped Africans in the English colonies that would become the United States, the institution of enslavement was foundational to the economy of every major city on the Eastern Seaboard

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This remarkable cell diversity derives from the basal airway stem cell by way of multiple branching lineages 1,2 , yet, the nature of these lineages, their transcriptional regulation, and the functional heterogeneity to which they lead, remain incompletely defined in humans