DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan building block Product Name Pomalidomide-5'-C1-acid Synonyms CAS

Product Name Pomalidomide-5'-C1-acid Synonyms CAS Number 2412056-27-8 Related CAS Molecular Formula C15H13N3O6 Molecular Weight 331

exhibited longer fluorescence lifetimes than its non-sulfonated counterparts

91 Purity (HPLC) >= 95% Physical Appearance Orange Solid Optical Properties Abs/Em Maxima: 502/511 nm Solubility DMSO Shipping Conditions Shipped on gel packs Storage Conditions Store at -20°C and protected from light Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

458 SMILES CC(C)(C)OC(=O)NCCN1CCN(CC1)C1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan building block Product Name Pomalidomide-5'-C1-acid Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC