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GPX4 utilizes reduced GSH as a critical substrate and oxidizes it to GSSH while converting PLOOH to fatty alcohol to suppress the LPO process (Lou et al., 2024)

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Finally, this pathway also modulates the tumor immune microenvironment through metabolic reprogramming, as illustrated in Figure 1

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It believes that high nutrient availability is central to effective supplementation

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doi: 10.1189/jlb.0302105 51 RuckesTSaulDVan SnickJHermineOGrassmannR

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