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Most users do not enter deep ketosis, but mild elevation of beta-hydroxybutyrate is common

Adverse events were rare in both groups, apart from the incidence of serious hypoglycemia in the lorcaserin group in those with diabetes managed using insulin or sulfonylureas (50, 51)

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As we have stated in previous rulemaking, consensus among affected parties can be reflected in various ways, including through the measure development process, through broad acceptance and use of the measure(s), and through public comment