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Its main function is the direct clearance of ROS and the restitution of other antioxidants such as vitamin E and ascorbic acid to their reduced forms.18 Our findings coincide with those of other studies that show that chronic hyperglycemia and oxidative stress in diabetic patients is accompanied by increased GSH oxidation with the consequent reduction of its serum levels.19 In saliva, Gumus et al

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This is accompanied by loss of the glycocalyx and a 60% increase in permeability of the vascular endothelium, a change that is even more pronounced in patients who die as a result of sepsis, indirectly demonstrating that sepsis leads to the degradation of the glycocalyx and a compensatory increase in glycocalyx synthesis by endothelial cells (60)