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However, recent evidence suggesting that ALAT activity is important for driving ECM formation through -ketoglutarate production in metastatic breast cancer cells, 40 has shed a different light on the role of amino acid synthesis

The study found that rats fed MCW exhibited higher nitric oxide synthase activity in the liver, increased plasma arginine concentrations, and elevated urinary nitrite levels compared to the L-arginine-treated group

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doi:10.1128/AEM.13.5.660-662.1965