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10.1021/acsptsci.9b00049 48 SenraH.BalaskasK.MahmoodiN.AslamT

The peptide crosses the blood-brain barrier and primarily acts through allosteric modulation of GABA-A receptors, producing anxiolytic effects similar to classical benzodiazepine drugs but without their associated side effects including sedation, muscle relaxation, dependence, or withdrawal syndrome