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Further, Hcy remethylation, primarily through a folate-dependent pathway, is markedly decreased in renal patients on hemodialysis

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity

This structure binds more tightly to DNA repair proteins than it does to normal double-stranded DNA, making the bulge structures a potential binding site for therapeutic drugs (Pieniazek et al., 2011)