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Get to an emergency room immediately if you experience: sudden loss of bladder or bowel control, sudden severe weakness in both legs, saddle anesthesia (numbness in the area that would touch a saddle), or sudden severe weakness or numbness in both arms

doi:10.1136/bmjopen-2022-065166

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jstage.jst.go.jpY Sato, Ouchi K, Funase Y, Yamauchi K (2013) T AizawaEndocrine journal, 2013jstage.jst.go.jp 60:12751280 Sugawara K, Okada Y, Hirota Y, Sakaguchi K, Ogawa W Relationship between metformin use and vitamin B12 status in patients with type 2 diabetes in Japan