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We are confident we have found an exceptional leader who will carry on the legacy of excellence cultivated by Larry Shapiro. Before joining Pitt in 2001, Perlmutter spent 15 years as a faculty member in the Department of Pediatrics at Washington University, where he was the first to hold the Donald Strominger Professorship of Pediatrics

and EC 4.2.2.1 distributes across PL8/PL16/PL31 families [1922]

R 3 and R 4 are independently selected from the group consisting of: hydrogen, C1-C12 alkyl, C1-C12 substituted alkyl, C1-C12 alkenyl, C1-C12 substituted alkenyl, C1-C12 alkynyl, C1-C12 substituted alkynyl, C3-C8 cycloalkyl, C3-C8 substituted cycloalkyl, C6-C10 aryl, C6-C10 substituted aryl, C3-C8 heterocycloalkyl, C3-C8 substituted heterocycloalkyl, C4-C10 heteroaryl, C4-C10 substituted heteroaryl, +CH(R a )OPO(OY)2, ^CH(R a )OPO(OY)(OH) and 3 and R 4 together are bonded to form a fused bicyclic ring system or a spirocyclic ring system