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Furthermore, the adenosine receptor A2aR, which is expressed on the surface of activated T cells, can be activated by adenosine and has been shown to dampen proximal T cell receptor signaling (102), diminish IL2-dependent proliferation of T cells (103), attenuate T cell cytotoxicity and cytokine production, induce T cell anergy and expression of inhibitory receptors (104), and promote the generation of regulatory T cells (105)

[DOI] [PMC free article] [PubMed] [Google Scholar] 84.Jin S, Guerrero-Juarez CF, Zhang L, Chang I, Ramos R, Kuan CH, et al

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