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doi: 10.1038/ng.2901, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 47.Mancina RM, Dongiovanni P, Petta S, Pingitore P, Meroni M, Rametta R, et al

The ability of the SC mechanism to act as a scavenger of free radicals was investigated in both a cellular system devoid of external influences and in activated human polymorphonuclear neutrophils

To evaluate the ability of molecules to interfere with aggregation of hCC while informing about cellular toxicity, cells were generated that produce and secrete WT and L68Q-hCC producing high-molecular weight complexes formed from the mutant protein